Short Communication 


Expression of HBeAg, HBsAg, anti- HBe and anti-HCV in individuals with elevated IL-10

Mathew Folaranmi Olaniyan.

Abstract
Background: Infections of hepatitis B and C virus can trigger anti-inflammatory process manifested through the expression of immune response products in the serum. Aim: This work was design to investigate the expression of HBeAg, HBsAg, anti- HBe and anti-HCV in individuals with elevated IL-10 to provide useful guide for the investigation of viral hepatitis for infection, prevention and control. Methods: Forty nine volunteers ( 23 63 years; n= 49 ; Female-23; Male - 26) with elevated plasma IL-10 were recruited for this study test subjects while fifty age matched apparently healthy volunteers ( 23 63 years; n= 50 ; Female-25; Male - 25) with normal plasma IL-10 were recruited as control subjects. HBeAg, HBsAg, anti- HBe, anti-HCV, IL-10, HIVP24Ag-Ab were determined by ELISA, Acid Fast Bacilli (AFB) by Ziehl Neelsen staining and Plasmodium identification by thick blood film Giemsa staining. Results: The frequency of HBeAg, HBsAg, anti- HBe and anti-HCV obtained in the volunteers with elevated IL-10 was 26.5%(13) HBeAg, 18.4%(9) HBsAg, 8.2%(4) Anti-HBe, 10%(5) anti-HCV, 16.5%(8) HBeAg + Anti-HBe , 12.2%(6) HBsAg + Anti-HBe while 6%(3) HBeAg, 8%(4) HBsAg, 16%(8) Anti-HBe, 6%(3) anti-HCV, 0% HBeAg + Anti-HBe , 14%(7) HBsAg + Anti-HBe was obtained in the control volunteers. Serum HBeAg, HBsAg, anti-HCV and HBeAg + anti-HBe were more frequent in volunteers with elevated IL-10 than the control subjects with normal IL-10 while serum anti-HBe and HBsAg + anti-HBe were more frequent in the control subjects compared with the results obtained from volunteers with elevated IL-10. Conclusion: Serum HBeAg, HBsAg, anti-HCV and HBeAg + anti-HBe in individuals with elevated IL-10 predict active and acute infection, poor prognosis, infection severity and infectiousness consequently require intervention for appropriate infection prevention and control.

Key words: HBeAg, HBsAg, anti- HBe, anti-HCV, IL-10


 
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Pubmed Style

Mathew Folaranmi Olaniyan. Expression of HBeAg, HBsAg, anti- HBe and anti-HCV in individuals with elevated IL-10. AJMS. 2021; 4(2): 14-17. doi:10.5455/ajms.47


Web Style

Mathew Folaranmi Olaniyan. Expression of HBeAg, HBsAg, anti- HBe and anti-HCV in individuals with elevated IL-10. http://www.ajms.tk/?mno=20932 [Access: February 19, 2021]. doi:10.5455/ajms.47


AMA (American Medical Association) Style

Mathew Folaranmi Olaniyan. Expression of HBeAg, HBsAg, anti- HBe and anti-HCV in individuals with elevated IL-10. AJMS. 2021; 4(2): 14-17. doi:10.5455/ajms.47



Vancouver/ICMJE Style

Mathew Folaranmi Olaniyan. Expression of HBeAg, HBsAg, anti- HBe and anti-HCV in individuals with elevated IL-10. AJMS. (2021), [cited February 19, 2021]; 4(2): 14-17. doi:10.5455/ajms.47



Harvard Style

Mathew Folaranmi Olaniyan (2021) Expression of HBeAg, HBsAg, anti- HBe and anti-HCV in individuals with elevated IL-10. AJMS, 4 (2), 14-17. doi:10.5455/ajms.47



Turabian Style

Mathew Folaranmi Olaniyan. 2021. Expression of HBeAg, HBsAg, anti- HBe and anti-HCV in individuals with elevated IL-10. Arabian journal of medical sciences, 4 (2), 14-17. doi:10.5455/ajms.47



Chicago Style

Mathew Folaranmi Olaniyan. "Expression of HBeAg, HBsAg, anti- HBe and anti-HCV in individuals with elevated IL-10." Arabian journal of medical sciences 4 (2021), 14-17. doi:10.5455/ajms.47



MLA (The Modern Language Association) Style

Mathew Folaranmi Olaniyan. "Expression of HBeAg, HBsAg, anti- HBe and anti-HCV in individuals with elevated IL-10." Arabian journal of medical sciences 4.2 (2021), 14-17. Print. doi:10.5455/ajms.47



APA (American Psychological Association) Style

Mathew Folaranmi Olaniyan (2021) Expression of HBeAg, HBsAg, anti- HBe and anti-HCV in individuals with elevated IL-10. Arabian journal of medical sciences, 4 (2), 14-17. doi:10.5455/ajms.47