Letter to the Editor 


Anticancer effect of trehalose by modulating oxidative stress, apoptosis and autophagy

Samah Kotb Nasr Eldeen, Mohammed El-Magd, Abeer Khamis, Wafaa Ibrahim, Afrah Salama.

Abstract
Trehalose is a novel disaccharide sugar that contains two glucose motifs. Nowadays, the major applications of trehalose have applied in the medical field. It has been investigated whether trehalose has inhibitory or protective effects on different types of tumor and non-tumor cells. Trehalose effect depends mainly on type of the target cells. Some studies reported that trehalose could potentially be employed as a novel anticancer agent that could be used safely and effectively to treat tumors by decreasing oxidative stress, autophagy, and increasing apoptosis. Some other studies found that trehalose is a potent autophagy inducer for some other cancer cell types. In this short review, we shed a light on the potential role played by trehalose as an anticancer, antioxidant or oxidative stress inducer, apoptotic or anti-apoptotic, and autophagy inhibitor or inducer agent.

Key words: Trehalose , Autophagy, Apoptosis, Oxidative stress.


 
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How to Cite this Article
Pubmed Style

Eldeen SKN, El-Magd M, Khamis A, Ibrahim W, AS, . Anticancer effect of trehalose by modulating oxidative stress, apoptosis and autophagy. AJMS. 2019; 2(1): 1-3. doi:10.5455/ajms.13


Web Style

Eldeen SKN, El-Magd M, Khamis A, Ibrahim W, AS, . Anticancer effect of trehalose by modulating oxidative stress, apoptosis and autophagy. http://www.ajms.tk/?mno=16187 [Access: June 25, 2019]. doi:10.5455/ajms.13


AMA (American Medical Association) Style

Eldeen SKN, El-Magd M, Khamis A, Ibrahim W, AS, . Anticancer effect of trehalose by modulating oxidative stress, apoptosis and autophagy. AJMS. 2019; 2(1): 1-3. doi:10.5455/ajms.13



Vancouver/ICMJE Style

Eldeen SKN, El-Magd M, Khamis A, Ibrahim W, AS, . Anticancer effect of trehalose by modulating oxidative stress, apoptosis and autophagy. AJMS. (2019), [cited June 25, 2019]; 2(1): 1-3. doi:10.5455/ajms.13



Harvard Style

Eldeen, S. K. N., El-Magd, . M., Khamis, . A., Ibrahim, . W., , . A. S. & (2019) Anticancer effect of trehalose by modulating oxidative stress, apoptosis and autophagy. AJMS, 2 (1), 1-3. doi:10.5455/ajms.13



Turabian Style

Eldeen, Samah Kotb Nasr, Mohammed El-Magd, Abeer Khamis, Wafaa Ibrahim, Afrah Salama, and . 2019. Anticancer effect of trehalose by modulating oxidative stress, apoptosis and autophagy. Arabian journal of medical sciences, 2 (1), 1-3. doi:10.5455/ajms.13



Chicago Style

Eldeen, Samah Kotb Nasr, Mohammed El-Magd, Abeer Khamis, Wafaa Ibrahim, Afrah Salama, and . "Anticancer effect of trehalose by modulating oxidative stress, apoptosis and autophagy." Arabian journal of medical sciences 2 (2019), 1-3. doi:10.5455/ajms.13



MLA (The Modern Language Association) Style

Eldeen, Samah Kotb Nasr, Mohammed El-Magd, Abeer Khamis, Wafaa Ibrahim, Afrah Salama, and . "Anticancer effect of trehalose by modulating oxidative stress, apoptosis and autophagy." Arabian journal of medical sciences 2.1 (2019), 1-3. Print. doi:10.5455/ajms.13



APA (American Psychological Association) Style

Eldeen, S. K. N., El-Magd, . M., Khamis, . A., Ibrahim, . W., , . A. S. & (2019) Anticancer effect of trehalose by modulating oxidative stress, apoptosis and autophagy. Arabian journal of medical sciences, 2 (1), 1-3. doi:10.5455/ajms.13